Mouse Anti-Cytokeratin 8-HRP MBS670012 from MyBioSource.com

Product Specs
ItemMouse Anti-Cytokeratin 8-HRP
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS670012
Quantity1 ml
ApplicationsELISA; Immunohistochemistry; Western Blot
Conjugate/TagHorseradish Peroxidase (HRP)
FormatHorseradish Peroxidase (HRP) Conjugate
TargetCytokeratin 8
IsotypeIgG2a
Molecular Weight53,704 Da
CloneSB37b1
HostMouse
ImmunogenKeratin 8 (55 kDa)1
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8). The two keratin types share only 30% sequence homology.2-6 Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 8 (55 kDa) belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with keratin 18. It is expressed in all simple type epithelia tissues (e.g., liver, pancreas, kidney, gut epithelial lining) but not in stratified squamous epithelia. Cytokeratin 8 is also present in the majority of adenocarcinomas and ductal carcinomas but is absent in squamous cell carcinomas.
The SB37b monoclonal antibody reacts specifically with cytokeratin 8 and recombinant C-terminal keratin 8
NCBI Full Gene Namekeratin 8, type II
NCBI Gene AliasesKO, CYK8, CK8, K2C8, CARD2, K8, CK-8
ClonalityMonoclonal